Summarize this content to 1000 words Exposure to environmental toxicants can lead to changes in DNA, RNA, proteins, and metabolites, but much work remains to understand exactly how those changes affect human biology and potentially lead to disease and ill health. NIEHS scientists joined others from academia, industry, and government who shared their research during the 51st annual meeting of the Environmental Mutagenesis and Genomics Society (EMGS) Sept. 12-16. NIEHS co-sponsored the
Summarize this content to 1000 words ExtramuralBy Megan Avakian PFAS linked with liver injury in children Exposure to per- and polyfluoroalkyl substances (PFAS) in the womb may increase liver injury risk in children, according to NIEHS-funded researchers. This study is the first to examine the impact of early life exposures to a PFAS mixture on child liver injury. PFAS, a large group of synthetic chemicals found in a variety of
Summarize this content to 1000 words Sills leads the Cellular and Molecular Pathology Branch, which provides toxicologic pathology leadership support for NIEHS. (Photo courtesy of Steve McCaw) Analyzing the entire genetic code of tumors in rodent cancer studies revealed that most rodent tumors had DNA mutation signatures that resemble those seen in human cancers, according to a new NIEHS study. A DNA mutation signature is the accumulation of cell mutations
Summarize this content to 1000 words The National Toxicology Program (NTP) published three new reports Sept. 25 on an herbicide, a class of pesticides, and a hormone-mimicking drug. The publications are among the first scoping reviews — a new type of NTP report. “Scoping reviews can be very helpful, giving a picture of where we have available data and where we don’t,” said Howdeshell. (Photo courtesy of Steve McCaw)“A scoping
Summarize this content to 1000 words Weis helped to organize the Federal Information Exchange, which will highlight the work of several scientists each month until February 2021. (Photo courtesy of Steve McCaw)Scientists from NIEHS and the U.S. Environmental Protection Agency (EPA) presented their latest research on per- and polyfluoroalkyl substances, or PFAS, in the second in a series of virtual Federal Information Exchanges Aug. 28. The exchanges are organized and
Summarize this content to 1000 words ExtramuralBy Adeline Lopez Correctional facilities' drinking water may put inmate health at risk Arsenic concentrations in drinking water in Southwestern U.S. correctional facilities may be twice as high as those in nearby communities, according to a recent NIEHS-funded study. Although arsenic levels in drinking water are generally higher in the Southwest than the rest of the U.S., this is the first study to document
Summarize this content to 1000 words 'We need to change the conversation and start talking about health disparities in a way that involves income inequality,' Olden said. (Photo courtesy of Steve McCaw)Kenneth Olden, Ph.D., served 14 years as NIEHS and National Toxicology Program director (1991-2005) and three as senior investigator and head of the Metastasis Group. When he left in 2008, he knew he would come back to visit, but
Summarize this content to 1000 words Mitochondria generate energy for cells and play important roles in metabolism, immunity, calcium signaling, and other processes, but they must interact with other organelles to function properly. Disruptions in such biological interaction can lead to cancer and neurodegenerative diseases. A new research project overseen by NIEHS could shed light on the important interplay between mitochondria and other organelles, and how errors can pave the
Summarize this content to 1000 words “My vision for the journal is a simple one: EHP is and should remain the premier international scholarly journal of the environmental health sciences,” said Kaufman after becoming editor-in-chief. (Photo courtesy of Joel Kaufman) Environmental Health Perspectives(https://ehp.niehs.nih.gov/) (EHP) Editor-in-Chief Joel Kaufman, M.D., was among 100 new members elected to the National Academy of Medicine (NAM) Oct. 19 in recognition of outstanding professional achievements and
Summarize this content to 1000 words After postdoctoral training at New York University and the National Institute of Child Health and Human Development, Negishi distinguished himself as head of the NIEHS Reproductive and Developmental Biology Laboratory and Pharmacogenetics Group. (Photo courtesy of Steve McCaw) To his long list of honors and awards, Masahiko Negishi, Ph.D., head of the NIEHS Pharmacogenetics Group, will add yet another — the title of National
