Summarize this content to 1000 words Lazar also directs the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania Perelman School of Medicine. (Photo courtesy of Mitchell Lazar)The latest NIEHS Distinguished Lecture focused on how an organism’s circadian rhythms, or the physiological processes that regularly change based on a 24-hour period, influence metabolism.Mitchell Lazar, M.D., Ph.D., the Willard and Rhoda Ware Professor in Diabetes and Metabolic Diseases at
Summarize this content to 1000 words “NIEHS extramural funding and efforts support more than 365 epidemiology studies that span 72 study populations,” said Joubert. (Photo courtesy of Steve McCaw)Scientists who study how chemicals and the environment may affect our health must grapple with the fact that real-world exposures involve mixtures. An individual’s everyday experience involves an array of substances from many sources, such as consumer products, diet, and occupational settings.
Summarize this content to 1000 words The National Institutes of Health (NIH) has funded a new coordinating center to transform how environmental drivers of health and disease are studied, so the knowledge can be used to personalize prevention and treatment strategies. By promoting innovation in new tools and methods, and investigator research networks, the NIEHS-led effort aims to establish exposomics as a core part of scientific and biomedical research across
Summarize this content to 1000 words At the Sept. 2-3 meeting of the Scientific Advisory Committee on Alternative Toxicological Methods(https://ntp.niehs.nih.gov/go/sacatm) (SACATM), committee members praised advances in use of computational methods to reduce animal use for chemical safety testing. They suggested resources and approaches that could be developed to further advance these tools, and identified testing areas where they could be applied.The committee encouraged member agencies of the Interagency Coordinating Committee
Summarize this content to 1000 words Rider co-chairs the NIEHS Combined Exposures/Mixtures working group. (Photo courtesy of Steve McCaw) Chemicals in consumer products and career options for early-career researchers who want to study how environmental agents may affect human health were among the topics discussed at the 2020 meeting of the North Carolina Society of Toxicology (NCSOT). Cynthia Rider, Ph.D., from the NIEHS Division of the National Toxicology Program, is
Summarize this content to 1000 words One of the most perplexing questions about SARS-CoV-2, the virus that causes COVID-19, is how it spreads so rapidly between people. Scientists know it can be transmitted by droplets from a sneeze or cough. But can it spread through aerosols, the smaller particles we give off when we exhale or speak? How long do infectious particles linger in the air? How far can they
Summarize this content to 1000 words NIEHS grantee Laura Niedernhofer, M.D., Ph.D., regularly visits with support groups for patients affected with the rare skin disorder she studies. She often tells participants that if anyone in their family is a budding scientist, to let her know and she will hire them to work in her lab.A California teen named Aimee Milota was the first to take her up on that offer.
Summarize this content to 1000 words Last spring, a team of researchers from NIEHS, North Carolina State University, and Texas A&M University created the Pandemic Vulnerability Index(https://covid19pvi.niehs.nih.gov/) (PVI) dashboard. Easy-to-understand, color-coded pie charts depict risk profiles for each United States county. The tool combines transmission data with information on socioeconomic and health care factors, and it is continuously updated.Huei-Chen Lee, Ph.D., K-12 science education program manager in the NIEHS Office
Summarize this content to 1000 words IntramuralBy Nicholas Alagna, Robin Arnette, Sanya Mehta, Victoria Placentra, and Prashant Rai Computational modeling identifies drug candidates for SARS-CoV-2 Scientists from the Division of the National Toxicology Program and their collaborators used computational modeling to probe databases and identify existing drugs that could be repurposed to fight SARS-CoV-2, the virus that causes COVID-19.Proteases are enzymes that break down proteins. An essential step in the
Summarize this content to 1000 words Research supported by NIEHS and the National Institute of Allergy and Infectious Diseases (NIAID) may help to explain why some people with COVID-19 become severely ill while others have no symptoms at all, and why more men than women die from the disease. The projects will increase knowledge of how genes and the environment can influence an individual’s susceptibility to COVID-19 and affect disease
